IONIZING RADIATION



Both for external and internal exposure, chromosome aberrations and/or micronuclei in lymphocytes seem to be the most sensitive for the follow-up of workers exposed to ionizing radiation.

For further information see the CRIOS website:
http://cdfc00.rug.ac.be/HealthRisk/ionizing_radiation/ionizing_radiation.htm



References:

Touil N., Elhajouji A., Thierens H., Kirsch-Volders M. "Analysis of chromosome loss and chromosome segregation in cytokinesis-blocked human lymphocytes: non-disjunction is the prevalent mistake in chromosome segregation produced by low dose exposure to ionizing radiation", Mutagenesis, 2000, 15(1): 1-7.  

Touil N., Aka P.V., Buchet J.P., Thierens H., Kirsch-Volders M. "Assessment of genotoxic effects related to chronic low level exposure to ionizing radiation using biomarkers for DNA damage and repair", Mutagenesis, 2002, 17(3): 223-232.