Polycyclic aromatic hydrocarbons (PAHs) constitute a large
class of chemicals with widespread occurence in the environment.
Benzo[a]pyrene has been extensively studied. It is a powerful mutagenic and
carcinogenic agent in various experimental systems and is also suspected to be a
significant health risk to humans. Therefore, benzo[a]pyrene is considered as a
model PAH.
Molecular Formula Benzo[a]pyrene: C20H12
sister chromatid exchanges in lymphocytes seem to be the most sensitive for the follow-up of workers exposed to polycyclic aromatic hydrocarbons
For further information see the CRIOS website: http://cdfc00.rug.ac.be/HealthRisk/PAHs/PAHs.htm
Reference:
Van Hummelen P., Gennart J.P., Buchet J.P., Lauwerys R., Kirsch-Volders M.; “Biological markers in PAH exposed workers and controls”, Mutation Research, 1993, 300: 231-239