Laboratory of Cell Genetics:

Research group of Micheline Volders

Publication list: M. Volders

2007

  • Fenech M, Bolognesi C, Kirsch-Volders M, Bonassi S, Zeiger E, Knasmuller S, Holland N. Harmonisation of the micronucleus assay in human buccal cells--a Human Micronucleus (HUMN) project (www.humn.org) initiative commencing in 2007. Mutagenesis 22:3-4(2007).
  • Godderis L, Aka P, Mateuca R, Kirsch-Volders M, Lison D, Veulemans H. Dose-dependent influence of genetic polymorphisms on DNA damage induced by styrene oxide, ethylene oxide and gamma-radiation. Toxicology 219:220-9(2006).
  • Taibi N, Aka P, Kirsch-Volders M, Bourgeois P, Fruhling J, Szpireer C. Radiobiological effect of 99mTechnetium-MIBI in human peripheral blood lymphocytes: ex vivo study using micronucleus/FISH assay. Cancer Lett 233:68-78(2006).
  • Kirsch-Volders M, Mateuca RA, Roelants M, Tremp A, Zeiger E, Bonassi S, Holland N, Chang WP, Aka PV, Deboeck M, Godderis L, Haufroid V, Ishikawa H, Laffon B, Marcos R, Migliore L, Norppa H, Teixeira JP, Zijno A, Fenech M. The effects of GSTM1 and GSTT1 polymorphisms on micronucleus frequencies in human lymphocytes in vivo. Cancer Epidemiol Biomarkers Prev 15:1038-42(2006).
  • Decordier I, Kirsch-Volders M. The in vitro micronucleus test: from past to future. Mutat Res 607:2-4(2006).
  • van Leeuwen DM, van Herwijnen MH, Pedersen M, Knudsen LE, Kirsch-Volders M, Sram RJ, Staal YC, Bajak E, van Delft JH, Kleinjans JC. Genome-wide differential gene expression in children exposed to air pollution in the Czech Republic. Mutat Res 600:12-22(2006).
  • Sarrif A, Kyrtopoulos SA, Autrup H, Farmer P, Kirsch-Volders M, Kleinjans JC, Knudsen LE, Mathar U, Wiegand HJ, Vrijhof H. Environmental genotoxins in children and adults: introduction and overview. Mutat Res 608:97-9(2006).
  • Kyrtopoulos SA, Sarrif A, Autrup H, Farmer P, Kirsch-Volders M, Kleinjans JCS, Knudsen LE., Mathar U, Wiegand HJ, Vrijhof H. Biomarkers and molecular epidemiology—present state and future trends: Introduction and overview. Mutat Res 600(1-2):1-2(2006)
  • Pedersen M, Vinzents P, Petersen JH, Kleinjans JC, Plas G, Kirsch-Volders M, Dostal M, Rossner P, Beskid O, Sram RJ, Merlo DF, Knudsen LE. Cytogenetic effects in children and mothers exposed to air pollution assessed by the frequency of micronuclei and fluorescence in situ hybridization (FISH): a family pilot study in the Czech Republic. Mutat Res 608:112-20(2006).
  • Mateuca R, Lombaert N, Aka PV, Decordier I, Kirsch-Volders M. Chromosomal changes: induction, detection methods and applicability in human biomonitoring. Biochimie 88:1515-31(2006).
  • Bonassi S, Znaor A, Ceppi M, Lando C, Chang WP, Holland N, Kirsch-Volders M, Zeiger E, Ban S, Barale R, Bigatti MP, Bolognesi C, Cebulska-Wasilewska A, Fabianova E, Fucic A, Hagmar L, Joksic G, Martelli A, Migliore L, Mirkova E, Scarfi MR, Zijno A, Norppa H, Fenech M. An increased micronucleus frequency in peripheral blood lymphocytes predicts the risk of cancer in humans. Carcinogenesis 14 (2006).

 

2005

  • Bonassi S, Ugolini D, Kirsch-Volders M, Stromberg U, Vermeulen R, Tucker JD. Human population studies with cytogenetic biomarkers: review of the literature and future prospectives. Environ Mol Mutagen 45:258-70(2005).
  • Decordier I, Cundari E, Kirsch-Volders M. Influence of caspase activity on micronuclei detection: a possible role for caspase-3 in micronucleation. Mutagenesis 20:173-9(2005).
  • Mateuca R, Aka PV, De Boeck M, Hauspie R, Kirsch-Volders M, Lison D. Influence of hOGG1, XRCC1 and XRCC3 genotypes on biomarkers of genotoxicity in workers exposed to cobalt or hard metal dusts. Toxicol Lett 156:277-88(2005).
  • Decordier I, Aka P, Lombaer N, Vanhauwaert A, Mateuca R, Kirsch-Volders M. Simplicity and complexity of genetic susceptibility in the occupational environment. Archives of Public Health 62:39-48(2004)
  • Godderis L, De Boeck M, Haufroid V, Emmery M, Mateuca R, Gardinal S, Kirsch-Volders M, Veulemans H, Lison D. Influence of genetic polymorphisms on biomarkers of exposure and genotoxic effects in styrene-exposed workers. Environ Mol Mutagen 44:293-303(2004).
  • De Boeck M, Kirsch-Volders M and Lison D. Corrigendum to "Cobalt and antimony : genotoxicity and carcinogenicity" (Mutat. Res. 533:135-152, 2003). Mutation Research 548:218-128 (2004)
  • M’Baku-Glöckel M, Aka PV and Kirsch-Volders M. Influence of individual genotypes on inflammatory response. Nutrition clinique et métabolisme 18:73-84 (2004)
  • Aka P, Mateuca R, Buchet JP, Thierens H, Kirsch-Volders M. Are genetic polymorphisms in OGG1, XRCC1 and XRCC3 genes predictive for the DNA strand break repair phenotype and genotoxicity in workers exposed to low dose ionising radiations? Mutat Res 556:169-81(2004)
  • Kirsch-Volders M, Sofuni T, Aardema M, Albertini S, Eastmond D, Fenech M, Ishidate MJR, Kirchner S, Lorge E, Morita T, Norppa H, Surrales J, Vanhauwaert A, Wakata A. Corrigendum to "Report from the in vitro micronucleus assay working group" (Mutat. Res. 540:153-163, 2003). Mutation Research 564:92-100 (2004)
  • Lombaert N, De Boeck M, Decordier I, Cundari E, Lison D, Kirsch-Volders M. Evaluation of the apoptogenic potential of hard metal dust (WC-Co), tungsten carbide and metallic cobalt. Toxicol Lett 154:23-34(2004).
  • Fenech M, Chang WP, Kirsch-Volders M, Holland N, Bonassi S, Zeiger E. HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures. Mutat Res 534:65-75(2003).
  • Fenech M, Bonassi S, Turner J, Lando C, Ceppi M, Chang WP, Holland N, Kirsch-Volders M, Zeiger E, Bigatti MP, Bolognesi C, Cao J, De Luca G, Di Giorgio M, Ferguson LR, Fucic A, Lima OG, Hadjidekova VV, Hrelia P, Jaworska A, Joksic G, Krishnaja AP, Lee TK, Martelli A, McKay MJ, Migliore L, Mirkova E, Muller WU, Odagiri Y, Orsiere T, Scarfi MR, Silva MJ, Sofuni T, Surralles J, Trenta G, Vorobtsova I, Vral A, Zijno A. Intra- and inter-laboratory variation in the scoring of micronuclei and nucleoplasmic bridges in binucleated human lymphocytes. Results of an international slide-scoring exercise by the HUMN project. Mutat Res 534:45-64(2003).
  • Bonassi S, Neri M, Lando C, Ceppi M, Lin YP, Chang WP, Holland N, Kirsch-Volders M, Zeiger E, Fenech M. Effect of smoking habit on the frequency of micronuclei in human lymphocytes: results from the Human MicroNucleus project. Mutat Res 543:155-66(2003).
    De Boeck M, Lombaert N, De Backer S, Finsy R, Lison D, Kirsch-Volders M. In vitro genotoxic effects of different combinations of cobalt and metallic carbide particles. Mutagenesis 18:177-86(2003).
  • Kirsch-Volders M, Vanhauwaert A, Eichenlaub-Ritter U, Decordier I. Indirect mechanisms of genotoxicity. Toxicol Lett 140-141:63-74(2003).
  • De Boeck M, Hoet P, Lombaert N, Nemery B, Kirsch-Volders M, Lison D. In vivo genotoxicity of hard metal dust: induction of micronuclei in rat type II epithelial lung cells. Carcinogenesis 24:1793-1800(2003).
  • Kirsch-Volders M, Lison D. Re: Hengstler, J.G., Bolm-Auorff, U., Faldum, A., Janssen, K., Reifenrath, M., Gotte, W., Jung, D., Mayer-Popken, O., Fuchs, J., Gebhard, S., Bienfait, H.G., Schlink, K., Dietrich, C., Faust, D., Epe, B. and Oesch, F. Occupational exposure to heavy metals: DNA damage induction and DNA repair inhibition prove co-exposures to cadmium, cobalt and lead as more dangerous than hitherto expected. Carcinogenesis, 2003, 24, 63-73. Carcinogenesis 24:1853-4; author reply 1855-7(2003).
  • Kirsch-Volders M, Sofuni T, Aardema M, Albertini S, Eastmond D, Fenech M, Ishidate M, Jr., Kirchner S, Lorge E, Morita T, Norppa H, Surralles J, Vanhauwaert A, Wakata A. Report from the in vitro micronucleus assay working group. Mutat Res 540:153-63(2003).
  • De Boeck M, Kirsch-Volders M, Lison D. Cobalt and antimony: genotoxicity and carcinogenicity. Mutat Res 533:135-52(2003).
  • Fenech M, Bonassi S, Turner J, Lando C, Ceppi M, Chang WP, Holland N, Kirsch-Volders M, Zeiger E, Bigatti MP, Bolognesi C, Cao J, De Luca G, Di Giorgio M, Ferguson LR, Fucic A, Lima OG, Hadjidekova VV, Hrelia P, Jaworska A, Joksic G, Krishnaja AP, Lee TK, Martelli A, McKay MJ, Migliore L, Mirkova E, Muller WU, Odagiri Y, Orsiere T, Scarfi MR, Silva MJ, Sofuni T, Surralles J, Trenta G, Vorobtsova I, Vral A, Zijno A. Erratum to “Intra- and inter-laboratory variation in the scoring of micronuclei and nucleoplasmic bridges in binucleated human lymphocytes. Results of an international slide-scoring exercise by the HUMN project. Mutat Res 534:45-64(2003).” Mutat Res 538(1-2):185-6.
  • Touil N, Aka PV, Buchet JP, Thierens H, Kirsch-Volders M. Assessment of genotoxic effects related to chronic low level exposure to ionizing radiation using biomarkers for DNA damage and repair. Mutagenesis 17:223-32(2002).
  • Kirsch-Volders M, Vanhauwaert A, De Boeck M, Decordier I. Importance of detecting numerical versus structural chromosome aberrations. Mutat Res 504:137-48(2002).
  • Decordier I, Dillen L, Cundari E, Kirsch-Volders M. Elimination of micronucleated cells by apoptosis after treatment with inhibitors of microtubules. Mutagenesis 17:337-44(2002).
  • Szasz A, Barna B, Gajda Z, Galbacs G, Kirsch-Volders M, Szente M. Effects of continuous low-dose exposure to organic and inorganic mercury during development on epileptogenicity in rats. Neurotoxicology 23:197-206(2002).
  • Kirsch-Volders M, Fenech M. Inclusion of micronuclei in non-divided mononuclear lymphocytes and necrosis/apoptosis may provide a more comprehensive cytokinesis block micronucleus assay for biomonitoring purposes. Mutagenesis 16:51-8(2001).
  • Vanhauwaert A, Vanparys P, Kirsch-Volders M. The in vivo gut micronucleus test detects clastogens and aneugens given by gavage. Mutagenesis 16:39-50(2001).
  • Bonassi S, Fenech M, Lando C, Lin YP, Ceppi M, Chang WP, Holland N, Kirsch-Volders M, Zeiger E, Ban S, Barale R, Bigatti MP, Bolognesi C, Jia C, Di Giorgio M, Ferguson LR, Fucic A, Lima OG, Hrelia P, Krishnaja AP, Lee TK, Migliore L, Mikhalevich L, Mirkova E, Mosesso P, Muller WU, Odagiri Y, Scarffi MR, Szabova E, Vorobtsova I, Vral A, Zijno A. HUman MicroNucleus project: international database comparison for results with the cytokinesis-block micronucleus assay in human lymphocytes: I. Effect of laboratory protocol, scoring criteria, and host factors on the frequency of micronuclei. Environ Mol Mutagen 37:31-45(2001).
  • Aardema MJ and Kirsch-Volders M. The in vitro micronucleus assay. in : Genetic Toxicology and Cancer Risk Assessment. 8:161-184, 2001 by M. Dekker, inc. New York-Basel (ed. Wai Nang Choy).
  • Lison D, De Boeck M, Verougstraete V, Kirsch-Volders M. Update on the genotoxicity and carcinogenicity of cobalt compounds. Occup Environ Med 58:619-25(2001).
  • Kirsch-Volders M, DE BOECK M, and Lison D. Génotoxicité et activité professionnelle. Encyclopédie Médicochirurgicale, 16-537C-10 and 16-537C-11, 2001.
  • De Boeck M, Touil N, De Visscher G, Vande PA, Kirsch-Volders M. Validation and implementation of an internal standard in comet assay analysis. Mutat Res 469:181-97(2000).
  • De Boeck M, Lardau S, Buchet JP, Kirsch-Volders M, Lison D. Absence of significant genotoxicity in lymphocytes and urine from workers exposed to moderate levels of cobalt-containing dust: a cross-sectional study. Environ Mol Mutagen 36:151-60(2000).
  • Kirsch-Volders M, Aardema M, Elhajouji A. Concepts of threshold in mutagenesis and carcinogenesis. Mutat Res 464:3-11(2000).
  • Touil N, Elhajouji A, Thierens H, Kirsch-Volders M. Analysis of chromosome loss and chromosome segregation in cytokinesis-blocked human lymphocytes: non-disjunction is the prevalent mistake in chromosome segregation produced by low dose exposure to ionizing radiation. Mutagenesis 15:1-7(2000).
  • Speit G, Autrup H, Crebelli R, Henderson L, Kirsch-Volders M, Madle S, Parry JM, Sarrif AM, Vrijhof H. Thresholds in genetic toxicology - concluding remarks. Mutat Res 464:149-53(2000).
  • Kirsch-Volders M, Sofuni T, Aardema M, Albertini S, Eastmond D, Fenech M, Ishidate M, Jr., Lorge E, Norppa H, Surralles J, von der Hude W, Wakata A. Report from the In Vitro Micronucleus Assay Working Group. Environ Mol Mutagen 35:167-72(2000).

 

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