Modulating peptide hydrogel strength through halogenation.
Vandeplassche, W.; Ballet, S.; Martin, C.; Hoogenboom, R.; Madder, A., J. Pept. Sci. 2018, 24, S109-S110.
Read more
Trifluoromethylated proline surrogates as part of 'Pro-Pro' turn-inducing templates for the design of beta-hairpin mimetics.
Gadais, C.; Van Holsbeeck, K.; Moors, S.; Feher, K.; Pytkowicz, J.; Martins, J.; De Proft, F.; Tourwe, D.; Brigaud, T.; Martin, C.; Chaume, G.; Ballet, S., J. Pept. Sci. 2018, 24, S117-S117.
Read more
The Neurokinins: Peptidomimetic Ligand Design and Therapeutic Applications.
Gadais, C.; Ballet, S., Current Medicinal Chemistry 2018, 25, 1-44.
Read more
Biodegradable Amphipathic Peptide Hydrogels as Extended-Release System for Opioid Peptides.
Martin, C.; Dumitrascuta, M.; Mannes, M.; Lantero, A.; Bucher, D.; Walker, K.; Van Wanseele, Y.; Oyen, E.; Hernot, S.; Van Eeckhaut, A.; Madder, A.; Hoogenboom, R.; Spetea, M.; Ballet, S., J. Med. Chem. 2018, 61, 9784-9789.
Read more
Biodegradable Amphipathic Peptide now on the cover of J Med Chem
Our latest work on the "Biodegradable Amphipathic Peptide Hydrogels as Extended-Release System for Opioid Peptides" has been featered on the cover of the journal of medicinal chemstry! For a full read, please check the publisher's page
Read more
Site-Specific Radioactive Labeling of Nanobodies.
Crauwels, M.; Massa, S.; Martin, C.; Betti, C.; Ballet, S.; Devoogdt, N.; Xavier, C.; Muyldermans, S. In Antibody Engineering: Methods and Protocols, Nevoltris, D.; Chames, P., Eds. Springer New York: New York, NY, 2018; pp 505-540.
Read more
A bifunctional-biased mu-opioid agonist-neuropeptide FF receptor antagonist as analgesic with improved acute and chronic side effects.
la Rochelle, A. D.; Guillemyn, K.; Dumitrascuta, M.; Martin, C.; Utard, V.; Quillet, R.; Schneider, S.; Daubeuf, F.; Willemse, T.; Mampuys, P.; Maes, B. U. W.; Frossard, N.; Bihel, F.; Spetea, M.; Simonin, F.; Ballet, S., Pain 2018, 159, 1705-1718.
Read more
Bromotryptophans and their incorporation in cyclic and bicyclic privileged peptides.
García-Pindado, J.; Willemse, T.; Goss, R.; Maes, B. U. W.; Giralt, E.; Ballet, S.; Teixidó, M., Biopolymers 2018, 109, e23112.
Read more
Chemical space screening around Phe3 in opioid peptides : Modulating µ versus δ agonism by Suzuki-Miyaura cross-couplings.
Willemse, T.; Eiselt, E.; Hollanders, K.; Schepens, W.; van Vlijmen, H. W. T.; Chung, N. N.; Blais, V.; Holleran, B.; Longpré, J.-M.; Schiller, P. W.; Maes, B. U. W.; Sarret, P.; Gendron, L.; Ballet, S., Bioorg. Med. Chem. Lett. 2018, 28, 2320-2323
Read more
PqsL uses reduced flavin to produce 2-hydroxylaminobenzoylacetate, a preferred PqsBC substrate in alkyl quinolone biosynthesis in Pseudomonas aeruginosa
S. L. Drees, S. Ernst, B. Belviso, N. Jagmann, U. Hennecke, S. Fetzner, J. Biol. Chem. 2018, 293, 9345-9357.
Read more
Nanobody-Enabled Reverse Pharmacology on G-Protein-Coupled Receptors.
Pardon, E.; Betti, C.; Laeremans, T.; Chevillard, F.; Guillemyn, K.; Kolb, P.; Ballet, S.; Steyaert, J., Angew. Chem. Int. Ed. 2018, 57, 5292-5295.
Read more
An Enantioselective Iodolactonization/Cross-Coupling Protocol for the Synthesis of Highly-Substituted Enol Lactones
C. Fricke, M. Wilking, C. G. Daniliuc, U. Hennecke, Eur. J. Org. Chem. 2018, 3158-3166.
Read more