Synthesis and in Vitro Evaluation of Stabilized and Selective Neuromedin U-1 Receptor Agonists.
De Prins, A.; Martin, C.; Van Wanseele, Y.; Tomboly, C.; Tourwe, D.; Caveliers, V.; Holst, B.; Van Eeckhaut, A.; Rosenkilde, M. M.; Smolders, I.; Ballet, S., ACS Med. Chem. Lett 2018, 9, 496-501.
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Indoloazepinone-Constrained Oligomers as Cell-Penetrating and Blood-Brain-Barrier-Permeating Compounds.
Van der Poorten, O.; Legrand, B.; Vezenkov, L. L.; Garcia-Pindado, J.; Bettache, N.; Knuhtsen, A.; Pedersen, D. S.; Sanchez-Navarro, M.; Martinez, J.; Teixido, M.; Garcia, M.; Tourwe, D.; Amblard, M.; Ballet, S, ChemBioChem 2018, 19, 696-705.
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Binding-Site Compatible Fragment Growing Applied to the Design of β2-Adrenergic Receptor Ligands.
hevillard, F.; Rimmer, H.; Betti, C.; Pardon, E.; Ballet, S.; van Hilten, N.; Steyaert, J.; Diederich, W. E.; Kolb, P., J. Med. Chem. 2018, 61, 1118-1129.
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Efficient one-pot synthesis of enantiomerically pure N-protected-alpha-substituted piperazines from readily available alpha-amino acids : N -protected-α-substituted piperazines from readily available α-amino acids.
Jida, M.; Ballet, S., New J. Chem. 2018, 42, 1595-1599.
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An Efficient One-Pot Synthesis of Chiral N-Protected 3-Substituted (Diketopiperazines via Ugi-4CR/De-Boc/Cyclization Process.
Jida, M.; Ballet, S., ChemistrySelect 2018, 3, 1027-1031.
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Zn-Catalyzed tert-Butyl Nicotinate-Directed Amide Cleavage as a Biomimic of Metallo-Exopeptidase Activity.
Wybon, C. C. D.; Mensch, C.; Hollanders, C.; Gadais, C.; Herrebout, W. A.; Ballet, S.; Maes, B. U. W., ACS Catalysis 2018, 8, 203-218.
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Development of potent and proteolytically stable human neuromedin U receptor agonists.
De Prins, A.; Martin, C.; Van Wanseele, Y.; Skov, L. J.; Tomboly, C.; Tourwe, D.; Caveliers, V.; Van Eeckhaut, A.; Holst, B.; Rosenkilde, M. M.; Smolders, I.; Ballet, S., Eur. J. Med. Chem. 2018, 144, 887-897.
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Efficient One-Pot Access to Trisubstituted 2-Benzazepin-3-ones as Constrained Pseudopeptide Analogues and Privileged Scaffolds.
Van der Poorten, O.; Jida, M.; Tourwé, D.; Ballet, S., Medicinal Chemistry 2018, 14, 400-408.
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Rapid construction of substituted 3-amino-1,5-benzothiazepin-4(5H)-one dipeptide scaffolds through an Ugi-4CR - Ullmann cross-coupling sequence.
Van der Poorten, O.; Van Den Hauwe, R.; Hollanders, K.; Maes, B. U. W.; Tourwe, D.; Jida, M.; Ballet, S., Org. Biomol. Chem. 2018, 16, 1242-1246.
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Antimicrobial peptides in frog poisons constitute a molecular toxin delivery system against predators.
Raaymakers, C.; Verbrugghe, E.; Hernot, S.; Hellebuyck, T.; Betti, C.; Peleman, C.; Claeys, M.; Bert, W.; Caveliers, V.; Ballet, S.; Martel, A.; Pasmans, F.; Roelants, K., Nature Communications 2017, 8, 1495
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χ-Space Screening of Dermorphin-Based Tetrapeptides through Use of Constrained Arylazepinone and Quinolinone Scaffolds.
Van der Poorten, O.; Van Den Hauwe, R.; Eiselt, E.; Betti, C.; Guillemyn, K.; Chung, N. N.; Hallé, F.; Bihel, F.; Schiller, P. W.; Tourwé, D.; Sarret, P.; Gendron, L.; Ballet, S., ACS Medicinal Chemistry Letters 2017, 8, 1177-1182.
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Analgesic Properties of Opioid/NK1 Multitarget Ligands with Distinct in Vitro Profiles in Naive and Chronic Constriction Injury Mice.
Starnowska, J.; Costante, R.; Guillemyn, K.; Popiolek-Barczyk, K.; Chung, N. N.; Lemieux, C.; Keresztes, A.; Van Duppen, J.; Mollica, A.; Streicher, J.; Vanden Broeck, J.; Schiller, P. W.; Tourwé, D.; Mika, J.; Ballet, S.; Przewlocka, B., ACS Chemical Neuroscience 2017, 8, 2315-2324.
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